Description

Semaglutide is a GLP-1 receptor agonist used in approved products for specific metabolic indications. The 1 mg strength appears within some injectable semaglutide regimens, but dose selection depends on the exact medicine and individual treatment plan.

 What is Semaglutide 1 mg Injection Pen?
A semaglutide 1 mg injection pen is a pen-format presentation containing semaglutide, a GLP-1 receptor agonist. A 1 mg dose is used within certain prescription regimens. It should not be started, substituted or adjusted without confirming the exact product and prescriber instructions.

How Semaglutide Works
Semaglutide binds to and activates GLP-1 receptors. In approved clinical use this can influence glucose-dependent insulin secretion, glucagon, gastric emptying, appetite and satiety.

About the 1 mg Strength
A higher numerical strength is not automatically a better or more effective choice for an individual patient. Dose escalation is intended to follow product-specific prescribing information and clinical assessment, including tolerability and treatment response.

Pen Use and Handling
Use only the device-specific Instructions for Use supplied with the pen. Check the label before each use, follow the prescribed injection schedule and never share a pen. If a pen is damaged, has been stored incorrectly or the medication does not appear as described by the manufacturer, contact the dispenser before use.

Storage
Follow the exact pen’s storage instructions. Requirements can change before and after first use. Protect medication from conditions prohibited by the label, and discard it when instructed even if medicine remains in the device.

Important Safety Information
Semaglutide is a GLP-1 receptor agonist and is not appropriate for every patient. Approved semaglutide products carry important warnings and contraindications. A healthcare professional should review the patient’s medical history, current medicines and treatment goals before use.

Common adverse reactions reported with approved semaglutide products are mainly gastrointestinal and can include nausea, vomiting, diarrhea, abdominal pain and constipation. Serious reactions can also occur, including pancreatitis, gallbladder problems, kidney injury related to volume depletion, severe gastrointestinal reactions, hypersensitivity reactions and complications of diabetic retinopathy in some patients.

Approved semaglutide labeling includes a boxed warning concerning the risk of thyroid C-cell tumors observed in rodents. Semaglutide products are contraindicated in people with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). The relevance of the rodent findings to humans has not been established.

Tell your healthcare professional about planned surgery or procedures requiring general anesthesia or deep sedation, and discuss pregnancy or plans for pregnancy. This summary is not a substitute for the complete prescribing information for the exact product supplied.

Who Should Speak With a Healthcare Professional Before Use?

• Anyone considering semaglutide should have the exact product, indication and dose assessed by a qualified healthcare professional.
• Discuss a personal or family history of medullary thyroid carcinoma (MTC) or MEN 2, previous pancreatitis, gallbladder disease, kidney problems, severe gastrointestinal disease, diabetic retinopathy and serious allergies.
• Tell the prescriber about insulin, sulfonylureas and other medicines that can affect blood glucose, as well as other oral medicines when using oral semaglutide.
• Discuss pregnancy, plans for pregnancy or breastfeeding before treatment. Current FDA labeling advises discontinuation of semaglutide at least 2 months before a planned pregnancy because of its long washout period.
• Tell healthcare providers about semaglutide before planned surgery or deep sedation because GLP-1 receptor agonists delay gastric emptying and pulmonary aspiration has been reported.

The information on this page is provided for general educational and product-information purposes and is not medical advice, diagnosis or a substitute for the prescribing information supplied with the medication. Semaglutide is a prescription medicine and may not be appropriate for everyone. Always follow the exact product label and instructions from a licensed healthcare professional. Seek urgent medical care for a suspected medical emergency.